Status:
RECRUITING
Urinary Vitamin C Loss in Diabetic Subjects
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Diabetes
Eligibility:
All Genders
18-65 years
Brief Summary
Several studies have reported that diabetic subjects have lower plasma vitamin C concentrations than non-diabetic subjects. Although urinary vitamin C loss in diabetic subjects was reported to be incr...
Detailed Description
Several studies have reported that diabetic subjects have lower plasma vitamin C concentrations than non-diabetic subjects. Although urinary vitamin C loss in diabetic subjects was reported to be incr...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- To be included in the study, study subjects should be:
- Aged 18-65 years.
- Either:
- Have no diagnosis of diabetes: "nondiabetic controls", or
- Have a diagnosis in their medical history of either Type 1 or Type 2 diabetes
- EXCLUSION CRITERIA (for outpatient study, arm 1)
- Exclusion criteria will include the following:
- Unable or unwilling to provide a signed and dated informed consent form
- Unable or unwilling to comply with study procedures and lifestyle considerations
- EXCLUSION CRITERIA (for inpatient studies, arms 2 and 3)
- Study participants interested in participating in Arms 2 and/or 3 will be excluded from this further participation if they meet any of the following:
- significant organ malfunction leading to clinical instability including liver disease, pulmonary disease, ischemic heart disease, heart failure, stroke, peripheral vascular disease, and anemia at investigator discretion
- other serious or chronic illness; history of serious or chronic illness; coronary artery disease, or peripheral vascular disease resulting in clinical instability
- pregnancy or lactation
- presence of other conditions which, in the judgment of the investigators, can influence vitamin C metabolism or vitamin C renal handling
Exclusion
Key Trial Info
Start Date :
April 11 2006
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT00071526
Start Date
April 11 2006
Last Update
January 5 2026
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892