Status:
COMPLETED
Classification of Cerebral Palsy Subtypes
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Cerebral Palsy
Eligibility:
All Genders
Brief Summary
This study, conducted at the National Institutes of Health and the Children's National Medical Center, will evaluate how well different physicians agree in how they classify cerebral palsy subtypes ba...
Detailed Description
The movement and posture abnormalities that are characteristic of cerebral palsy are associated with underlying abnormalities of muscle tone, including dystonia, spasticity, and rigidity. The subtypes...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Children 6 to 18 years of age
- Children must be previously diagnosed with cerebral palsy
- Children born at any gestational age will be eligible.
- Lesions must be pre-, peri- or post-natal and acquired before 2 years of age
- Lesions must be non-progressive
- Patients must be able to voluntarily move their upper and lower limbs
- EXCLUSION CRITERIA:
- Any subject who is pregnant
- Children with an underlying known genetic or chromosomal disorder
- Children with clearly identified familial or non-familial syndromes (without known chromosomal or genetic defect)
- Cerebral lesions acquired after 2 years of age
- Patients with progressive or neurodegenerative disorders
- Patients with spinal disorders in the absence of cerebral lesions
- Patients with sickle cell disease
- Patients with cerebral lesions caused by emboli associated with congenital cardiac lesions
- Patients with severe cognitive deficits who cannot follow simple verbal commands
- Patients incapable of voluntary movement of either upper or lower limbs due to contractures.
- Patients with prior rhizotomy
- Patients with prior orthopedic (bone or soft tissue) surgery or serial casting
- Patients with severe postural abnormalities who cannot maintain supported sitting.
Exclusion
Key Trial Info
Start Date :
November 1 2003
Trial Type :
OBSERVATIONAL
End Date :
August 1 2005
Estimated Enrollment :
115 Patients enrolled
Trial Details
Trial ID
NCT00072800
Start Date
November 1 2003
End Date
August 1 2005
Last Update
March 4 2008
Active Locations (1)
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1
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, Maryland, United States, 20892