Status:
COMPLETED
Spinal Cord Plasticity
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Healthy
Eligibility:
All Genders
21-65 years
Brief Summary
This study will examine the role of the spinal cord in improving leg movements after physical training in healthy people. The results of this study may be helpful in developing new rehabilitation ther...
Detailed Description
Objectives We aim to determine whether the development of a motor memory in the human spinal cord circuitry (expressed as a down regulation of the monosynaptic soleus H reflex) after a brief period o...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Healthy volunteers (age 21 to 65 years) who are willing to participate and who are considered able to cylce for 16 minutes based on neurological and physical exams will be eligible for the study. Reproductive age women with a negative pregnancy test.
- EXCLUSION CRITERIA:
- Subjects with history of heart condition, unresponsive arterial hypertension, diabetes, chronic back pain, sciatica, peripheral neuropathy, rheumatoid arthritis, active joint deformity of arthritic origin, alcohol or drug abuse, psychiatric disorder requiring hospitalization or prolonged treatment, head injury with loss of consciousness, epilepsy. Subjects with history of hyperthyroidism or individuals receiving drugs acting primarily on the central nervous system or disorders of the blood coagulation system. Pregnant women.
Exclusion
Key Trial Info
Start Date :
December 1 2003
Trial Type :
OBSERVATIONAL
End Date :
May 20 2008
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT00073606
Start Date
December 1 2003
End Date
May 20 2008
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892