Status:
COMPLETED
Treatment of Depression in Adults
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Depression
Eligibility:
All Genders
18-66 years
Phase:
PHASE4
Brief Summary
This study will determine how certain features of depressed individuals affect their responses to depression treatment.
Detailed Description
Major depression is a serious condition that can have devastating functional consequences. Although numerous depression studies have been conducted, understanding of how best to achieve long-term reco...
Eligibility Criteria
Inclusion
- Diagnosis of Major depression
Exclusion
- History of manic or hypomanic episodes
- History of schizophrenia or schizoaffective disorder
- Diagnosis of anorexia nervosa or bulimia nervosa
- Current psychosis
- Drug and/or alcohol dependence or abuse within 3 months prior to study entry. Participants with episodic abuse related to mood disorders will not be excluded.
- Diagnosis of antisocial personality disorder
- Diagnosis of organic affective syndrome and uncontrolled medical illness
- Pregnancy
- Require inpatient treatment for suicidal risk or psychosis
- History of an inability to tolerate any of the study treatments
- Currently receiving treatment with an effective antidepressant
Key Trial Info
Start Date :
May 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2007
Estimated Enrollment :
290 Patients enrolled
Trial Details
Trial ID
NCT00073697
Start Date
May 1 2003
End Date
October 1 2007
Last Update
January 11 2012
Active Locations (2)
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1
Western Psychiatric Institute and Clinic - Depression Prevention Program
Pittsburgh, Pennsylvania, United States, 15213
2
The University of Pisa
Pisa, Italy