Status:
COMPLETED
Timing of Surgery and Chemotherapy in Treating Patients With Newly Diagnosed Advanced Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Lead Sponsor:
Royal College of Obstetricians and Gynecologists
Conditions:
Fallopian Tube Cancer
Ovarian Cancer
Eligibility:
FEMALE
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Giving a chemotherapy drug before surgery may shrink the tumor so that it ca...
Detailed Description
OBJECTIVES: * Determine the feasibility of a randomized trial to determine the impact of the timing of surgery and chemotherapy in patients with newly diagnosed advanced ovarian epithelial, primary p...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Newly diagnosed advanced ovarian epithelial, primary peritoneal, or fallopian tube cancer
- Clinical and imaging evidence of a pelvic mass with extrapelvic metastases within the past 4 weeks
- Serum CA 125/CEA ratio \> 25
- Plans to receive carboplatin-based chemotherapy
- PATIENT CHARACTERISTICS:
- Age
- Adult
- Performance status
- Not specified
- Life expectancy
- Not specified
- Hematopoietic
- Not specified
- Hepatic
- Not specified
- Renal
- Not specified
- Other
- Considered fit to undergo protocol treatment and follow-up
- No other prior or concurrent malignancy that would preclude study treatment or comparisons
- PRIOR CONCURRENT THERAPY:
- Biologic therapy
- Not specified
- Chemotherapy
- See Disease Characteristics
- Endocrine therapy
- Not specified
- Radiotherapy
- Not specified
- Surgery
- Not specified
Exclusion
Key Trial Info
Start Date :
September 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT00075712
Start Date
September 1 2003
Last Update
August 12 2013
Active Locations (70)
Enter a location and click search to find clinical trials sorted by distance.
1
Stoke Mandeville Hospital
Aylesbury-Buckinghamshire, England, United Kingdom, HP21 8AL
2
North Devon District Hospital
Barnstaple, England, United Kingdom, EX31 4JB
3
Royal United Hospital
Bath, England, United Kingdom, BA1 3NG
4
Blackpool Victoria Hospital
Blackpool, England, United Kingdom, FY3 8NR