Status:
COMPLETED
Evaluation and Treatment of Patients With Connective Tissue Disease
Lead Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions:
Connective Tissue Disorders
Osteogenesis Imperfecta
Eligibility:
All Genders
Up to 70 years
Brief Summary
This study offers evaluation and treatment of patients with a suspected connective tissue disorder. The protocol is not designed to test new treatments; rather, patients receive standard care. The stu...
Detailed Description
This protocol seeks to formalize the application of accepted diagnostic and therapeutic measures in the study of individuals with known or suspected bone-related connective tissue disorders, including...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Individuals with a suspected bone-related connective tissue disorder, as indicated by signs including, but not limited to, fractures, low bone density, asymmetric overgrowth of long bone
- OR
- Apparently unaffected, healthy family members of individuals with a suspected bone-related connective tissue disorder.
- Ages to be enrolled are from 0-70 years old, with only viable neonates accepted at age 0 years.
- EXCLUSION CRITERIA:
- Individuals who, in the opinion of the Investigator, are unable to comply with the protocol or have medical conditions that would potentially increase the risk of participation.
- For both affected individuals and apparently healthy family members, no exclusions are based on age, gender, ethnicity or race, religion, or English-language ability. Those who are pregnant, whether affected or unaffected, will be excluded from any exam that includes
- radiation, but not excluded from the study overall.
Exclusion
Key Trial Info
Start Date :
May 18 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT00076830
Start Date
May 18 2004
Last Update
July 10 2025
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892