Status:
COMPLETED
Language and Emotional Function in Patients With Temporal Lobe Epilepsy
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Epilepsy
Temporal Lobe
Eligibility:
All Genders
18+ years
Brief Summary
This study uses functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) to examine how the brain processes tasks involving language and emotion in normal volunteers and in pati...
Detailed Description
OBJECTIVES: Epilepsy surgery is emerging as a potent therapeutic intervention for a large group of patients with uncontrolled temporal lobe epilepsy, particularly when performed early in the course of...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Patient Group:
- Temporal lobe epilepsy (right-sided, left-sided foci) with or without lesion on a structural MRI scan.
- Native English speaker.
- Age 18 years or older.
- Signed informed consent.
- Volunteer Group:
- Native English speaker.
- Age 18 years or older.
- Signed informed consent.
- EXCLUSION CRITERIA:
- Patient Group:
- Medical or technical contraindications to MRI procedures (e.g. no braces, pacemakers, cochlear devices, surgical clips, etc;
- History of mental retardation;
- Pregnancy;
- Claustrophobia;
- Inability to comply with the protocol.
- Volunteer Group:
- Medical or technical contraindications to MRI procedures (e.g. no braces, pacemakers, cochlear devices, surgical clips, etc.);
- History of neurologic or psychiatric disease or a learning or attention disorder or mental retardation.
- Pregnancy.
- Claustrophobia.
- Inability to comply with the protocol.
Exclusion
Key Trial Info
Start Date :
April 9 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 27 2010
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00081432
Start Date
April 9 2004
End Date
April 27 2010
Last Update
July 2 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892