Status:
COMPLETED
Genetics of Ankylosing Spondylitis
Lead Sponsor:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Conditions:
Spondylitis
Ankylosing Spondylitis
Eligibility:
All Genders
Brief Summary
Ankylosing spondylitis (AS) is a chronic inflammatory disease that affects the joints between the vertebrae of the spine and the joints between the spine and the pelvis. The purpose of this study is t...
Detailed Description
AS is a chronic inflammatory disease that eventually causes the affected vertebrae to fuse or grow together. The cause of AS is unknown, but genetic factors seem to play a role. Risk factors include a...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Meet modified New York criteria for ankylosing spondylitis (AS)
- AS as confirmed by X-rays of sacroiliac joints (between the pelvis and spine)
- At least two siblings in family with AS
- Parents of the participants with AS have the option of also being enrolled
Exclusion
Key Trial Info
Start Date :
September 1 1999
Trial Type :
OBSERVATIONAL
End Date :
December 1 2006
Estimated Enrollment :
1600 Patients enrolled
Trial Details
Trial ID
NCT00081562
Start Date
September 1 1999
End Date
December 1 2006
Last Update
February 21 2008
Active Locations (2)
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1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
2
University of Texas - Health Science Center at Houston
Houston, Texas, United States, 77030