Status:

COMPLETED

Caspofungin for the Treatment of Non-blood Candida Infections (0991-045)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Candidiasis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Candida is the most common fungal pathogen identified in hospitalized patients. This study will seek to enroll adult patients (18 years of age or older) with invasive Candida infections (involving dee...

Eligibility Criteria

Inclusion

  • All patients must have at least 1 positive culture for Candida species obtained from an otherwise sterile, non-blood body site within 96 hours of the study entry.
  • The patient must also have clinical evidence of Candida infection (e.g., oral temperature \>100 degrees Fahrenheit, signs of inflammation from infected site, systolic blood pressure \<90) within 96 hours of study entry.
  • The patient must be at least 18 years old, and if a woman of child bearing potential, must have a negative serum or urine pregnancy test sensitive to 25 IU HCG prior to enrollment.

Exclusion

  • Patients whose only site of Candida infection was the bloodstream.

Key Trial Info

Start Date :

May 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2006

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT00083343

Start Date

May 1 2004

End Date

February 1 2006

Last Update

February 23 2017

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