Status:

COMPLETED

A Study of Xeloda (Capecitabine) in Women With High-Risk Breast Cancer

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Breast Cancer

Eligibility:

FEMALE

18-70 years

Phase:

PHASE3

Brief Summary

This 2 arm study will compare the efficacy and safety of Taxotere + Xeloda, versus Taxotere alone, following a regimen of Adriamycin plus Cytoxan in women with high-risk breast cancer. Following 4 cyc...

Eligibility Criteria

Inclusion

  • female patients 18-70 years of age;
  • adenocarcinoma of the breast;
  • previous invasive breast cancer if diagnosed \>5 years before entering study;
  • no evidence of metastatic disease.

Exclusion

  • history of severe hypersensitivity reaction to Taxotere;
  • previous treatment with anthracycline, anthracenedione (mitoxantrone), or taxane;
  • treatment with fluoropyrimidine (5-fluorouracil) within the last 5 years.

Key Trial Info

Start Date :

August 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2012

Estimated Enrollment :

2611 Patients enrolled

Trial Details

Trial ID

NCT00089479

Start Date

August 1 2002

End Date

May 1 2012

Last Update

December 21 2012

Active Locations (1)

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1

Houston, Texas, United States, 77060