Status:
COMPLETED
Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood Cancers
Lead Sponsor:
ViaCell
Conditions:
Acute Lymphocytic Leukemia
Acute Myeloid Leukemia
Eligibility:
All Genders
12-60 years
Phase:
PHASE1
PHASE2
Brief Summary
This study hopes to show that specially treated umbilical cord cells, called stem cells, can be safely given to a person after they receive chemoradiation therapy or chemotherapy for their illness. Du...
Eligibility Criteria
Inclusion
- Do not have identical or 5/6 related matched bone marrow, peripheral blood or umbilical cord
- Stable disease and lack of unrelated donor
- Acute myeloid leukemia (AML) in 2nd or subsequent complete remission or first remission with high risk features
- ALL in 2nd or subsequent remission or first remission with high risk features
- Myelodysplastic syndrome (MDS)
- Non-Hodgkin Lymphoma (NHL)
- Chronic Myelogenous Leukemia (CML)
- Adequate function of heart, liver, kidneys and lungs
Exclusion
- Females who are pregnant
- Poor ability to perform daily activities
- Weight under 40 kilograms (88 pounds)
- AML caused by chemoradiation
- Prior stem cell transplant
- Uncontrolled infection at time of transplant
- Active fungal infection
- HIV infection
- Primary myelofibrosis
- Receiving other research drugs
- Unable to provide informed consent
Key Trial Info
Start Date :
March 1 2004
Trial Type :
INTERVENTIONAL
End Date :
October 1 2006
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00089596
Start Date
March 1 2004
End Date
October 1 2006
Last Update
April 12 2007
Active Locations (4)
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1
Loyola University Medical Center
Maywood, Illinois, United States, 60153
2
Indiana University Cancer Center
Indianapolis, Indiana, United States, 46202
3
Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
4
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263