Status:

COMPLETED

A Safety and Efficacy Study for Infliximab (Remicade) in Patients With Ulcerative Colitis

Lead Sponsor:

Centocor, Inc.

Conditions:

Ulcerative Colitis

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the effectiveness and safety of infliximab (Remicade) in patients with Ulcerative Colitis. Infliximab (Remicade) targets specific proteins in the body's immune...

Detailed Description

This study is designed to investigate the safety and effectiveness of infliximab in adult patients with active ulcerative colitis. The purpose of this study is to see if the symptoms of ulcerative col...

Eligibility Criteria

Inclusion

  • Patients must have had ulcerative colitis of at least 3 months' duration at screening, confirmed by the biopsy taken at screening
  • Patients must have active colitis confirmed during the screening sigmoidoscopy
  • Patients must have active disease.

Exclusion

  • Patient must not be likely to require surgical removal of all or part of the colon within 12 weeks of beginning the study
  • Patient must not require, or required within the 2 months prior to beginning the study, surgery for active gastrointestinal bleeding, peritonitis, intestinal obstruction, or intra-abdominal or pancreatic abscess requiring surgical drainage

Key Trial Info

Start Date :

May 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2007

Estimated Enrollment :

364 Patients enrolled

Trial Details

Trial ID

NCT00096655

Start Date

May 1 2002

End Date

August 1 2007

Last Update

May 17 2011

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