Status:

COMPLETED

Study of the Feasibility to Derive Vaccine From Tumor Tissue in Patients With Non-Small Cell Lung Cancer

Lead Sponsor:

Agenus Inc.

Conditions:

Non-Small-Cell Lung Carcinoma

Lung Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Antigenics is enrolling patients in a Phase II study testing the feasibility to derive an autologous investigational vaccine (HSPPC-96) from the tumor tissue of patients with resectable non-small cell...

Detailed Description

Antigenics is enrolling patients in a Phase II study testing the feasibility to derive an autologous investigational vaccine (HSPPC-96) from the tumor tissue of patients with resectable non-small cell...

Eligibility Criteria

Inclusion

  • This is a summary of criteria. Only the Principal Investigator can determine eligibility.
  • Suspected non-small cell lung cancer, Stage IB, Stage II, or Stage IIIA
  • Tumor size \> 3x3 cm or equivalent to a 9 cm² lesion
  • Scheduled surgery with curative intent
  • At least 18 years of age
  • Must not be pregnant or breast feeding
  • Agree to not receive any other investigative agent at any time while enrolled in this study

Exclusion

  • Previous treatment for non-small cell lung cancer
  • Clinical signs or symptoms of brain metastases
  • History of immune suppression or autoimmune disorder
  • Severe active infection or other serious medical illness, that in the opinion of the Principal Investigator, would prevent study completion
  • Other malignancies in the past 5 years, except adequately treated in situ cervix carcinoma or non-melanoma skin cancer

Key Trial Info

Start Date :

September 1 2003

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00098085

Start Date

September 1 2003

Last Update

March 9 2009

Active Locations (1)

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1

London, United Kingdom

Study of the Feasibility to Derive Vaccine From Tumor Tissue in Patients With Non-Small Cell Lung Cancer | DecenTrialz