Status:

TERMINATED

A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Pain

Bone Neoplasm

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This 2 arm study will compare the efficacy of intravenous Bondronat with that of zoledronic acid in patients with malignant bone disease experiencing moderate to severe pain. Patients will be randomiz...

Eligibility Criteria

Inclusion

  • patients with malignant bone disease;
  • patients with moderate to severe pain.

Exclusion

  • patients who have received a bisphosphonate within 3 weeks from the signing of the informed consent;
  • patients receiving concurrent investigational therapy, or who have received investigational therapy within 30 days of the first scheduled day of dosing;
  • untreated esophagitis or gastric ulcers;
  • recent or pre-scheduled radiotherapy to bone;
  • patients who are pregnant or breast-feeding.

Key Trial Info

Start Date :

July 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

163 Patients enrolled

Trial Details

Trial ID

NCT00099203

Start Date

July 1 2005

End Date

December 1 2007

Last Update

August 16 2017

Active Locations (72)

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Page 1 of 18 (72 locations)

1

Birmingham, Alabama, United States, 35205

2

Sedona, Arizona, United States, 86336

3

Ocoee, Florida, United States, 34761

4

Macon, Georgia, United States, 31201