Status:
COMPLETED
Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans
Lead Sponsor:
National Institute on Aging (NIA)
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Center for Research Resources (NCRR)
Conditions:
Aging
Obesity
Eligibility:
All Genders
65-78 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether DHEA replacement therapy decreases abdominal fat and improves insulin sensitivity.
Detailed Description
Studies on rats and mice have shown that the adrenal hormone dehydroepiandrosterone (DHEA) reduces abdominal visceral fat and protects against insulin resistance. This study was done to learn if DHEA ...
Eligibility Criteria
Inclusion
- 65 to 78 years old
- Physically healthy
- Non-smoker
- On stable medications for at least 6 months
- Stable body weight for the past year
Exclusion
- Serious active medical problems
- Hormone therapy
- Abnormal PSA (prostate specific antigen) in men
Key Trial Info
Start Date :
June 1 2001
Trial Type :
INTERVENTIONAL
End Date :
February 1 2004
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00099697
Start Date
June 1 2001
End Date
February 1 2004
Last Update
December 11 2009
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110