Status:
UNKNOWN
Rhenium Re 188 P2045 in Patients With Lung Cancer Who Have Received or Refused to Receive Prior Chemotherapy
Lead Sponsor:
Andarix Pharmaceuticals
Conditions:
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Eligibility:
All Genders
21+ years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to determine the maximum dose that is safely tolerated of the experimental drug Rhenium Re 188 P2045. This will be done by first treating patients at relatively low doses ...
Detailed Description
We want to learn more about the side effect profile of both Technetium Tc 99m P2045 and Rhenium Re 188 P2045 and will do that by observing you closely after you receive the drug and by conducting mult...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Has histologically or cytologically documented Non-Small-Cell Lung Cancer (NSCLC) or Small-Cell Lung Cancer (SCLC) and has advanced or recurrent IIIb or IV NSCLC (adenocarcinoma, squamous cell carcinoma, large cell, mixed or not otherwise specified) or disseminated or recurrent SCLC or any lung cancer which has local recurrence.
- Has documentation of progressive disease following prior chemotherapy or who refused to receive standard chemotherapy.
- Has measurable tumor (at least 1 cm unidimensionally) in a previously non-irradiated area or, if in previously irradiated area, a substantial increase in size of tumor, based on CT scan within 8 weeks prior to enrollment; tumor in previously irradiated area only if it has increased by 50% or more from previous minimal diameter AND it is more than 8 weeks from the radiation.
Exclusion
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 20 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00100256
Start Date
January 1 2004
End Date
April 20 2025
Last Update
November 7 2022
Active Locations (2)
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1
Iowa City, Iowa, United States, 52242
2
Baltimore, Maryland, United States, 21201