Status:
COMPLETED
Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF)
Lead Sponsor:
Cystic Fibrosis Foundation
Conditions:
Cystic Fibrosis
Eligibility:
All Genders
8-14 years
Phase:
NA
Brief Summary
Zinc deficiency has occasionally been reported in CF, but the need for additional zinc is unclear. We will examine the effect of additional zinc supplements on zinc absorption, zinc excretion, zinc ba...
Detailed Description
Overt zinc deficiency presents with features of acrodermatitis enteropathica (AE) including diarrhea, dermatitis, growth failure, and poor immune function. AE has been described as a complication of c...
Eligibility Criteria
Inclusion
- Aged 8-14 years old
- Have clinical pancreatic insufficiency (defined as the need for pancreatic enzyme replacement)
- Have no other medical problems except CF (and its complications)
- Weigh \> 25kg
Exclusion
- Are taking any medicines (other than for CF and its complications)
- Have known pancreatic endocrine dysfunction
- Are taking more than 10 mg/d elemental zinc supplements
- Have had major GI surgery, including gut resection, but not including surgery for decompression of meconium ileus (if this was the presenting feature of CF)
Key Trial Info
Start Date :
May 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2007
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00104494
Start Date
May 1 2004
End Date
September 1 2007
Last Update
July 30 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Baylor College of Medicine
Houston, Texas, United States, 77030