Status:

COMPLETED

Genetic Characterization of Parkinson's Disease

Lead Sponsor:

National Institute of Neurological Disorders and Stroke (NINDS)

Conditions:

Parkinson Disease

PD

Eligibility:

All Genders

Brief Summary

This study will explore the risks and causes of Parkinson's disease, a chronic progressive nervous system disorder. Patients typically have tremors, muscle weakness and a shuffling gait. Patients wit...

Detailed Description

Parkinson's disease (PD) was noted to have a familial component as early as 1880. More recently, the discovery of several genetic factors influencing Parkinson's disease has emphasized the importance ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Individuals with Parkinson's disease OR
  • Family members of an individual diagnosed with Parkinson's disease OR
  • Healthy adult controls obtained through the NIH Clinical Research Volunteers Program (CVRP) or other healthy control volunteers who come forward.
  • EXCLUSION CRITERIA:
  • Under the age of 18 years of age OR
  • Individuals with Parkinsonism secondary to a specific cause such as toxin exposure, birth injury, head injury, or brain infection such as encephalitis.
  • Healthy volunteers with a medical history or first degree family history of Parkinson's disease.

Exclusion

    Key Trial Info

    Start Date :

    March 1 2005

    Trial Type :

    OBSERVATIONAL

    End Date :

    November 1 2005

    Estimated Enrollment :

    2500 Patients enrolled

    Trial Details

    Trial ID

    NCT00105131

    Start Date

    March 1 2005

    End Date

    November 1 2005

    Last Update

    March 4 2008

    Active Locations (1)

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    National Institute of Neurological Disorders and Stroke (NINDS)

    Bethesda, Maryland, United States, 20892