Status:
COMPLETED
Clinical and Genetic Studies of Familial Exudative Vitreoretinopathy
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Exudatiaon
Avascular Retina
Eligibility:
All Genders
1+ years
Brief Summary
This study will examine the extent of the vision problem in familial exudative vitreoretinopathy (FEVR) and try to identify the genes responsible for this hereditary eye disorder. Patients with FEVR h...
Detailed Description
Background: Familial exudative vitreoretinopathy (FEVR) is a rare hereditary disorder of the retinal vasculature characterized by abrupt cessation of the growth of peripheral retinal capillaries. FEVR...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- The patients must carry the clinical diagnosis of familial exudative vitreoretinopathy. Whenever a patient fulfills the above requirement additional family members can be included in the study as participants. Subjects of any ethnic background, gender, age, sexual orientation, or health status will be included.
- EXCLUSION CRITERIA:
- Prematurity and supplemental oxygen use at bith can cause a clinical picture similar to familial exudative vitreoretinopathy. The existence of either of those factors in the past medical history of a patient will necessitate exclusion from the study. Since fluorescein angiography is crucial for the correct diagnosis of the syndrome, patients with a previous allergic reaction to fluorescein dye will also be excluded. Patients inability or unwillingness to provide a blood sample is an exclusion criterion as well.
Exclusion
Key Trial Info
Start Date :
March 18 2005
Trial Type :
OBSERVATIONAL
End Date :
November 1 2006
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT00106756
Start Date
March 18 2005
End Date
November 1 2006
Last Update
July 2 2017
Active Locations (2)
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1
Izaak Walton Killam Grace Health Centre
Halifax, Canada
2
St. James University
Leeds, United Kingdom