Status:
COMPLETED
Radiation Therapy in Treating Women With Localized Breast Cancer
Lead Sponsor:
Institute of Cancer Research, United Kingdom
Conditions:
Breast Cancer
Eligibility:
FEMALE
50-120 years
Phase:
NA
Brief Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in different ways and giving it after surgery may kill any tumor cells that remain after surgery. PU...
Detailed Description
OBJECTIVES: * Compare late normal tissue effects of standard vs 2 different dose levels of hypofractionated adjuvant whole breast radiotherapy, in terms of changes in photographic breast appearance, ...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of invasive carcinoma of the breast
- Localized disease
- Pathological tumor size \< 3.0 cm in diameter
- Axillary node negative
- At average or low risk of local tumor recurrence
- Must have undergone prior breast-preserving surgery
- No prior mastectomy
- Complete microscopic resection of tumor
- Hormone receptor status:
- Not specified
- PATIENT CHARACTERISTICS:
- Age
- 50 and over
- Sex
- Female
- Menopausal status
- Not specified
- Performance status
- Not specified
- Life expectancy
- Not specified
- Hematopoietic
- Not specified
- Hepatic
- Not specified
- Renal
- Not specified
- Other
- Fertile patients must use effective contraception
- PRIOR CONCURRENT THERAPY:
- Biologic therapy
- Not specified
- Chemotherapy
- No prior neoadjuvant or adjuvant cytotoxic chemotherapy
- Endocrine therapy
- Not specified
- Radiotherapy
- No concurrent lymphatic radiotherapy
- No concurrent radiotherapy boost to the breast
- Surgery
- See Disease Characteristics
Exclusion
Key Trial Info
Start Date :
October 5 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 9 2017
Estimated Enrollment :
917 Patients enrolled
Trial Details
Trial ID
NCT00107497
Start Date
October 5 2004
End Date
March 9 2017
Last Update
February 27 2019
Active Locations (19)
Enter a location and click search to find clinical trials sorted by distance.
1
Sussex Cancer Centre at Royal Sussex County Hospital
Brighton, England, United Kingdom, BN2 5BE
2
Cumberland Infirmary
Carlisle, England, United Kingdom, CA2 7HY
3
Cheltenham General Hospital
Cheltenham, England, United Kingdom, GL53 7AN
4
Royal Devon and Exeter Hospital
Exeter, England, United Kingdom, EX2 5DW