Status:

TERMINATED

Research Study for Patients With Metastatic Renal Cell Carcinoma

Lead Sponsor:

Bayer

Conditions:

Carcinoma, Renal Cell

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This study has been designed to study patients diagnosed with advanced renal cell cancer with the primary tumor in place.

Eligibility Criteria

Inclusion

  • Life expectancy of at least 12 weeks
  • Clinical, radiographic, or pathologic diagnosis of metastatic renal cell carcinoma (RCC). All renal cell histologies are allowed- Acceptable surgical risk in the judgment of the study investigator and consulting urological surgeon
  • At least one uni-dimensional measurable lesion outside the planned nephrectomy specimen
  • Patients who have an ECOG performance status of 0 or 1

Exclusion

  • History of bleeding diathesis or unexpected surgical bleeding- Patients currently receiving treatment with or having a requirement for therapeutic anticoagulation
  • Prior therapy for RCC. Palliative radiation therapy for painful or unstable bone metastases is permitted provided that there is measurable metastatic disease outside the radiation field
  • Known history of HIV infection- Symptomatic metastatic brain or meningeal tumors, unless the patient is \> 6 months from definitive therapy, has a CT or MRI scan within 6 weeks of study entry negative for brain metastases and is clinically stable with respect to the tumor at the time of study entry

Key Trial Info

Start Date :

November 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2006

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT00110344

Start Date

November 1 2005

End Date

June 1 2006

Last Update

October 11 2013

Active Locations (1)

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1

Boston, Massachusetts, United States, 02115-6084