Status:
COMPLETED
TEAM: Testosterone Supplementation and Exercise in Elderly Men
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Healthy
Eligibility:
MALE
60+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to evaluate the effects of testosterone supplementation (AndroGel) on body composition, strength, endurance, cognition, and function in older men.
Detailed Description
Studies suggest that testosterone (T) replacement in healthy elderly men has beneficial effects on body composition, muscle, bone, memory, and behavior, but the risks of chronic treatment, especially ...
Eligibility Criteria
Inclusion
- Generally healthy, untrained men 60 years or older with low-normal testosterone levels (200-350ng/dL)
- Must reside in the Denver metro area
Exclusion
- Prostate/breast cancer
- Unable to exercise safely
- severe obesity (\>34 body mass index \[BMI\])
- Polycythemia
- Diabetes
- Use of drugs that could affect T levels
- Cognitive dysfunction (MMSE less than 24)
- PSA above the age-adjusted normal level or AUA greater than 19
- Unable to pass stress test due to active CAD
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2010
Estimated Enrollment :
167 Patients enrolled
Trial Details
Trial ID
NCT00112151
Start Date
January 1 2005
End Date
November 1 2010
Last Update
September 2 2020
Active Locations (1)
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1
University of Colorado Health Sciences Center
Denver, Colorado, United States, 80262