Status:
COMPLETED
Effects of Hormonal Infertility Treatment on Cognition in Pre-Menopausal Women
Lead Sponsor:
National Institute on Aging (NIA)
Conditions:
Infertility
Eligibility:
FEMALE
25+ years
Brief Summary
The purpose of this study is to examine the effects of marked alterations in ovarian steroid hormones on cognitive functions in women. Sex hormones and stress hormones of women awaiting or undergoing ...
Detailed Description
Much of our understanding of the effects of ovarian steroid hormones on cognitive functioning comes from studies of changes in cognitive function associated with hormone replacement therapy (HRT) in p...
Eligibility Criteria
Inclusion
- Women 25 years and older, who are still ovulating
- Residing in Maryland or the Washington DC metropolitan area
- Healthy women in one of the following groups:
- 1\) beginning or currently undergoing IVF infertility treatments with GnRH-a alone,
- 2\) beginning or currently undergoing IVF infertility treatments with GnrH-a plus sex steroid stimulating hormones,
- 3\) going through the adoption process, or
- 4\) taking monophasic oral contraceptives for at least six months
Exclusion
- English not the primary language
- Women who are peri- or post-menopausal
- Women who are currently taking anti-depressants or have a history of head injury or neurological/psychiatric condition
- Groups 1 \& 2 (IVF) - women who are undergoing Inter-uterine insemination as an infertility treatment
- Group 3 (ADPT) - women who underwent hormonal infertility treatments within the previous 6 months
- Group 4 (OC) - women on progesterone only (mini-pill) oral contraceptives
Key Trial Info
Start Date :
September 1 2003
Trial Type :
OBSERVATIONAL
End Date :
November 1 2006
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00113867
Start Date
September 1 2003
End Date
November 1 2006
Last Update
December 11 2009
Active Locations (1)
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1
National Institute on Aging (NIA), Harbor Hospital
Baltimore, Maryland, United States, 21225