Status:

COMPLETED

A Study of Albuferon and Ribavirin in Interferon Naive Subjects With Chronic Hepatitis C Genotype 1

Lead Sponsor:

Human Genome Sciences Inc.

Conditions:

Hepatitis C, Chronic

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

The purpose of the study is to evaluate the efficacy and safety of Albuferon in combination with ribavirin in interferon (IFN) alfa treatment-naïve subjects with chronic hepatitis C genotype 1. The st...

Eligibility Criteria

Inclusion

  • Key
  • Interferon treatment naive subjects with chronic hepatitis C, HCV genotype 1.
  • Compensated liver disease
  • Key

Exclusion

  • Pregnant or lactating female or males with a pregnant partner.
  • A positive test for serum antibodies to the human immunodeficiency virus (HIV-1) or serum hepatitis B virus surface antigen (HBsAg).
  • A history of moderate, severe or uncontrolled psychiatric disease.
  • A history of immunologically mediated disease, seizure disorder, chronic cardiac disease, chronic pulmonary disease, hemoglobinopathy, coagulopathy, or malignancy.

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2007

Estimated Enrollment :

458 Patients enrolled

Trial Details

Trial ID

NCT00115908

Start Date

May 1 2005

End Date

May 1 2007

Last Update

November 7 2013

Active Locations (87)

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Page 1 of 22 (87 locations)

1

Royal Prince Alfred Hospital

Camperdown, New South Wales, Australia, 2050

2

Concord Repatriation General Hospital

Concord, New South Wales, Australia, 2139

3

John Hunter Hospital

New Lambton Heights, New South Wales, Australia, 2305

4

Westmead Hospital

Westmead, New South Wales, Australia, 2145