Status:

COMPLETED

Vaccination in the Peripheral Stem Cell Transplant Setting for Acute Myelogenous Leukemia

Lead Sponsor:

Cell Genesys

Conditions:

Acute Myelogenous Leukemia

Eligibility:

All Genders

18-60 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate clinical and laboratory safety associated with the administration of GVAX leukemia vaccine and to determine the feasibility of generation of GVAX leukemia vacc...

Eligibility Criteria

Inclusion

  • Initial diagnosis of de novo AML with no preexisting hematologic dysplasia for more than 3 months.
  • No prior therapy except leukapheresis or less than 72 hours of hydroxyurea.

Exclusion

  • Prior myelodysplastic disorder, or treatment-related leukemia.
  • Prior myeloproliferative disease.
  • Acute promyelocytic leukemia (APL).
  • Prior chemotherapy for a malignant or nonmalignant disorder.

Key Trial Info

Start Date :

March 1 2001

Trial Type :

INTERVENTIONAL

End Date :

January 1 2006

Estimated Enrollment :

55 Patients enrolled

Trial Details

Trial ID

NCT00116467

Start Date

March 1 2001

End Date

January 1 2006

Last Update

December 24 2007

Active Locations (4)

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Page 1 of 1 (4 locations)

1

University of California, San Francisco

San Francisco, California, United States, 94143

2

University of Chicago

Chicago, Illinois, United States, 60637

3

Johns Hopkins University

Baltimore, Maryland, United States, 21231

4

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02115