Status:

TERMINATED

Photodynamic Therapy (PDT) for Lower Urinary Tract Symptoms (PLUS)

Lead Sponsor:

QLT Inc.

Conditions:

Prostatic Hyperplasia

Eligibility:

MALE

21+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to determine if transurethral photodynamic therapy with lemuteporfin has a therapeutic effect on lower urinary tract symptoms due to an enlarged prostate. Photodynamic th...

Detailed Description

This is a multi-center, randomized, sham-controlled, double-blind, dose-finding study in parallel groups of subjects with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH)....

Eligibility Criteria

Inclusion

  • Men 21 years of age and older.
  • Subjects with LUTS due to BPH with AUA SI scores of 13 and over and Qmax between 5 and 15 mL/sec.
  • Subjects with urethral treatment length of at least 25 mm.

Exclusion

  • Subjects who have had previous minimally invasive or surgical treatment for BPH.
  • Subjects who have unsuitable prostate dimensions.

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

End Date :

December 1 2006

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT00116571

Start Date

May 1 2005

End Date

December 1 2006

Last Update

October 3 2006

Active Locations (9)

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Page 1 of 3 (9 locations)

1

San Bernardino Urological Associates

San Bernardino, California, United States, 92404

2

Regional Urology, LLC

Shreveport, Louisiana, United States, 71106

3

Drs Werner, Murdock & Francis PA Urology Associates

Greenbelt, Maryland, United States, 20770

4

Lawrenceville Urology

Lawrenceville, New Jersey, United States, 08648