Status:

COMPLETED

A Study to Evaluate the Effectiveness of Aranesp® for Cancer Patients With Anemia

Lead Sponsor:

Amgen

Conditions:

Anemia

Neoplasms

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this trial is to assess the effectiveness of Aranesp® administered at 300 mcg every 3 weeks (q3w) in achieving therapeutic objectives of anemia treatment (achieving and maintaining hemo...

Eligibility Criteria

Inclusion

  • Subjects with non-myeloid malignancy - Anemia (Hgb less than 11.0 g/dL) due to cancer chemotherapy - Receiving chemotherapy and expected to receive at least 8 additional weeks of chemotherapy - Adequate renal function - Adequate liver function

Exclusion

  • Subjects with acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML), or myelodysplastic syndromes (MDS) - Unstable cardiac disease - Active bleeding - Active systemic or chronic infection - Severe active chronic inflammatory disease - Other hematologic disorder associated with anemia - Uncontrolled hypertension - Known iron or nutritional deficiency - Known positive test for human immunodeficiency virus (HIV) infection - History of pure red cell aplasia - History of positive antibody response to any erythropoietic agent - Erythropoietin therapy within 4 weeks before screening - RBC transfusions within 2 weeks prior to screening

Key Trial Info

Start Date :

January 1 2004

Trial Type :

INTERVENTIONAL

End Date :

April 1 2005

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT00117039

Start Date

January 1 2004

End Date

April 1 2005

Last Update

October 15 2008

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