Status:
COMPLETED
Multi-Detector Spiral Computed Tomography Alone Versus Combined Strategy With Lower Limb Compression Ultrasonography in Outpatients Suspected of Pulmonary Embolism
Lead Sponsor:
University Hospital, Geneva
Conditions:
Pulmonary Embolism
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The main hypothesis for this study is that the diagnostic approach of pulmonary embolism (PE) by evaluation of clinical probability, D-dimer test dosage and multi-detector helical computed tomography ...
Detailed Description
Suspected pulmonary embolism \[PE\] is a frequent clinical problem and remains a diagnostic challenge. The diagnostic approach of PE relies on sequential diagnostic tests, such as plasma D-dimer measu...
Eligibility Criteria
Inclusion
- All outpatients admitted to the emergency ward for suspected pulmonary embolism, defined as acute onset of new or worsening shortness of breath or chest pain without another obvious etiology, will be included in the study, provided they meet all other criteria and they have signed an informed consent form.
Exclusion
- PE suspicion raised more than 24 hours after admission to the hospital
- Absence of informed consent
- Life expectancy of less than 3 months
- Geographic inaccessibility for follow-up
- Pregnancy
- Patients anticoagulated for a disease other than venous thromboembolism (for instance, atrial fibrillation)
- Patients allergic to contrast medium
- Impaired renal function (creatinine clearance less than 30 ml/min, as calculated by the Cockroft formula)
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
End Date :
October 1 2006
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT00117169
Start Date
January 1 2005
End Date
October 1 2006
Last Update
October 15 2012
Active Locations (1)
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1
Geneva University Hospital
Geneva, Canton of Geneva, Switzerland, 1205