Status:
UNKNOWN
Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia
Lead Sponsor:
Radboud University Medical Center
Conditions:
Preeclampsia
Eligibility:
FEMALE
Phase:
PHASE4
Brief Summary
A history of preeclampsia is associated with a low plasma volume and higher sympathetic activity. Methyldopa will suppress sympathetic activity to normal values. In this study, the researchers will te...
Detailed Description
This is a randomized double-blind placebo controlled cross-over study in formerly preeclamptic women with a contracted plasma volume. The researchers will test the effect of methyldopa on the cardiova...
Eligibility Criteria
Inclusion
- Primiparous
- History of preeclampsia
- Low plasma volume
Exclusion
- Thrombophilia
- Hypertension
- Auto-immune disorder
- Insulin dependent diabetes mellitus
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2008
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT00117546
Start Date
September 1 2005
End Date
December 1 2008
Last Update
June 8 2010
Active Locations (1)
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1
Radboud University Nijmegen Medical Center
Nijmegen, Netherlands