Status:
COMPLETED
Radiologic Evaluation and Breast Density (READ)
Lead Sponsor:
Kaiser Permanente
Conditions:
Breast Cancer
Eligibility:
FEMALE
45-80 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether cessation of hormone replacement therapy for one or two months before a screening mammogram will improve its performance by decreasing breast density.
Detailed Description
This randomized, controlled trial is designed to test whether short-term (1-2 months) HRT cessation will sufficiently lower breast density to decrease the proportion of women who receive a recommendat...
Eligibility Criteria
Inclusion
- 1 or more prior screening mammograms at Group Health Cooperative within the past 2 years
- Currently taking HRT
- Taking HRT at prior screening mammogram
- Due for a screening mammogram
Exclusion
- BI-RADS breast density of 1 (entirely fat)
- Previous cardiovascular events (heart surgery, catheterization, stent bypass, angioplasty, stroke, DVT)
- Previous breast cancer
- History of breast implants
- Breast reduction since last mammogram
- Mastectomy
- History of using Tamoxifen or Raloxifene
- Declined contact or use of data for research
Key Trial Info
Start Date :
November 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2007
Estimated Enrollment :
1704 Patients enrolled
Trial Details
Trial ID
NCT00117663
Start Date
November 1 2004
End Date
November 1 2007
Last Update
April 4 2024
Active Locations (1)
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1
Group Health Research Institute
Seattle, Washington, United States, 98101