Status:
COMPLETED
Nasal Ocular Reflexes Contribute to Eye Symptoms
Lead Sponsor:
University of Chicago
Collaborating Sponsors:
GlaxoSmithKline
Conditions:
Rhinitis, Allergic, Seasonal
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Eye symptoms of tearing, redness and itching frequently occur in patients with allergic rhinitis or hayfever. The purpose of this trial is to study whether placing an allergen (a substance that causes...
Detailed Description
Symptoms of conjunctivitis (tearing, redness and itching) frequently occur in patients with allergic rhinitis. The pathophysiology underlying these symptoms remains to be elucidated. The symptoms prob...
Eligibility Criteria
Inclusion
- History of grass and/or ragweed allergic rhinitis.
- Positive skin test to grass and/or ragweed antigen.
- Positive response to screening nasal challenge.
Exclusion
- Physical signs or symptoms suggestive of renal, hepatic or cardiovascular disease.
- Pregnant or lactating women.
- Upper respiratory infection within 14 days of study start.
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
End Date :
October 1 2006
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00117832
Start Date
March 1 2005
End Date
October 1 2006
Last Update
September 5 2013
Active Locations (1)
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1
University of Chicago
Chicago, Illinois, United States, 60637