Status:

COMPLETED

The Prevention of Osteoporosis in Premenopausal and Newly Postmenopausal (Up to 8 Years) Women With Breast Cancer Following Chemotherapy (REBBeCA Study)

Lead Sponsor:

University of Pittsburgh

Collaborating Sponsors:

Procter and Gamble

Aventis Pharmaceuticals

Conditions:

Osteoporosis

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effectiveness of once weekly risedronate in the prevention and treatment of bone loss in premenopausal and newly menopausal women with breast cancer who ha...

Detailed Description

Breast cancer is a significant public health problem accounting for approximately 30% of new cancers diagnosed annually. Much advancement has been made in the treatment of these cancers which has sign...

Eligibility Criteria

Inclusion

  • Pre- and newly postmenopausal (up to 8 years) women ages 18 and older
  • Breast cancer treated with chemotherapeutic agents, with or without tamoxifen/aromatase inhibitors
  • Negative pregnancy test

Exclusion

  • Stage 4 breast cancer
  • Any illness or medications known to affect bone metabolism
  • History of osteoporosis or history of vertebral or hip fractures
  • Kidney stones in the past 5 years
  • Active peptic ulcer disease

Key Trial Info

Start Date :

May 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2006

Estimated Enrollment :

87 Patients enrolled

Trial Details

Trial ID

NCT00118508

Start Date

May 1 2003

End Date

July 1 2006

Last Update

August 13 2015

Active Locations (1)

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University of Pittsburgh Medical Center (GCRC)

Pittsburgh, Pennsylvania, United States, 15213