Status:

COMPLETED

Long-Term Supervised Treatment Interruption in HIV-Infected Patients

Lead Sponsor:

French National Agency for Research on AIDS and Viral Hepatitis

Conditions:

HIV Infections

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This trial is aimed at studying the safety of long term supervised treatment interruption in HIV infected patients with CD4 over 350/mm3 and plasma HIV RNA under 50 000/mL. Another aim of this study i...

Detailed Description

The limitations of the drugs used against HIV include their toxicity, their tolerability, their propensity to induce resistance when not taken with absolute regularity and their cost. Treatment interr...

Eligibility Criteria

Inclusion

  • Males and non pregnant females
  • 18 years of age and older
  • Who have confirmed laboratory diagnosis of HIV infection
  • Started on first line antiretroviral treatment with CD4 over 350/mm3 and plasma HIV RNA below 50 000/mL
  • Ongoing Antiretroviral therapy at inclusion with CD4 over 450/mm3 and plasma HIV RNA below 5000/mL

Exclusion

  • HBV-HIV co-infection receiving lamivudine therapy
  • Ongoing immunotherapy including IL2, interferon or HIV specific vaccine
  • Pregnancy or project of pregnancy

Key Trial Info

Start Date :

February 1 2003

Trial Type :

INTERVENTIONAL

End Date :

May 1 2007

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT00118677

Start Date

February 1 2003

End Date

May 1 2007

Last Update

August 30 2007

Active Locations (1)

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Service d'immunologie Clinique, Höpital Européen Georges Pompidou

Paris, France, 75015