Status:
COMPLETED
Characterization of Serial Magnetic Resonance Spectroscopy Imaging in Patients With Malignant Glioma Undergoing Radiotherapy
Lead Sponsor:
AHS Cancer Control Alberta
Conditions:
Malignant Glioma
Eligibility:
All Genders
18+ years
Brief Summary
Malignant glioma is the most common primary brain tumor in adults. Despite aggressive therapy, less than 40% of these patients are expected to live beyond 5 years. The radiologic imaging of these tumo...
Detailed Description
Background: Malignant glioma is the most common primary brain tumor in adults. Despite aggressive therapy, less than 40% of these patients are expected to live beyond 5 years. External beam radiother...
Eligibility Criteria
Inclusion
- Patients must be older than 18 years of age.
- Patients must have histologically proven malignant glioma of the brain.
- Patients must have bi-directionally measurable enhancing residual disease by T1 weighted image.
- Patients must be willing to undergo high dose radiotherapy to the brain for the treatment of their glial tumor.
- Patients must be willing and able to comply with all study requirements.
- The patient or legally authorized representative must fully understand all elements of informed consent, and sign the consent document.
Exclusion
- History of previous RT to the head and neck region.
- History of lupus, scleroderma or RT hypersensitivity.
- Co-existing medical condition precluding radiotherapy.
- Psychiatric conditions precluding informed consent.
- Medical or psychiatric conditions precluding MR studies (eg. pacemaker, aneurysm clips, neuro stimulator, cochlear implant, severe claustrophobia/anxiety).
Key Trial Info
Start Date :
May 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2015
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT00125697
Start Date
May 1 2005
End Date
June 1 2015
Last Update
July 18 2016
Active Locations (1)
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1
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2