Status:

COMPLETED

A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Malignant Lymphoma (0683-030)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Lymphoma

Eligibility:

All Genders

20-75 years

Phase:

PHASE1

Brief Summary

The primary purpose of this trial is to determine the maximum tolerated dose (MTD), or the maximum acceptable dose (MAD) and evaluate the dose limiting toxicity (DLT) of oral vorinostat in patients wi...

Eligibility Criteria

Inclusion

  • Patients who relapsed after complete or partial response, or ineffective in previous chemotherapy

Exclusion

  • Patients with history of chemotherapy, antibody therapy, radiotherapy, during the previous 4 weeks (6 months for radioisotope-labeled antibody)
  • Any uncontrolled concomitant illness
  • Are pregnant or breast-feeding
  • Serious drug or food allergy

Key Trial Info

Start Date :

June 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2012

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT00127140

Start Date

June 1 2005

End Date

April 1 2012

Last Update

September 28 2015

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A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Malignant Lymphoma (0683-030) | DecenTrialz