Status:

COMPLETED

Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep

Lead Sponsor:

Penn State University

Collaborating Sponsors:

National Honey Board

Conditions:

Cough

Respiratory Tract Infections

Eligibility:

All Genders

2-18 years

Phase:

PHASE1

Brief Summary

Cough is the most common reason for an acute care doctor's visit in the United States. Cough can affect sleep for both coughing children and their parents. The American Academy of Pediatrics does not ...

Detailed Description

Cough is one of the most common reasons for a doctor's visit in the United States and may be the most bothersome symptom for children with colds. It is particularly annoying at night because it can in...

Eligibility Criteria

Inclusion

  • Ages 2 to \<18 years
  • Cough due to upper respiratory tract infection (URI), as determined by physical examination
  • Sleep difficulty on the preceding night attributed to frequent cough
  • Ability to swallow liquids
  • Willingness of the child's guardian to participate in a survey

Exclusion

  • Signs/symptoms of more serious/treatable disease
  • Itchy, watery eyes
  • Frequent sneezing, tachypnea (respiratory rate \>95th percentile) or labored breathing; symptoms for 8 or more days.
  • History of asthma in the past 2 years
  • Chronic lung disease, or seizure disorder
  • Allergic reaction to honey or DM
  • Selective serotonin reuptake inhibitors (SSRIs) or anti-malarial drugs
  • Diabetes mellitus or signs/symptoms of insulin resistance

Key Trial Info

Start Date :

September 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2006

Estimated Enrollment :

105 Patients enrolled

Trial Details

Trial ID

NCT00127686

Start Date

September 1 2005

End Date

December 1 2006

Last Update

November 24 2017

Active Locations (1)

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1

Penn State Milton S. Hershey Medical Center

Hershey, Pennsylvania, United States, 17545