Status:
TERMINATED
Nitroprusside for Prevention of no-Reflow in Primary Angioplasty
Lead Sponsor:
Soroka University Medical Center
Conditions:
Myocardial Infarction
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
In patients admitted with acute myocardial infarction, there is a total occlusion of a coronary artery. Even after emergency catheterization and angioplasty, in some patients, the resumed blood flow i...
Detailed Description
Inadequate myocardial tissue perfusion despite successful relief of the culprit occlusion and restoration of epicardial coronary flow for ST-segment elevation acute myocardial infarction (STEMI) resul...
Eligibility Criteria
Inclusion
- Acute ST elevation myocardial infarction (MI) patients planned for primary PCI
- Diagnostic angiography demonstrating a TIMI flow grade \<3 in the coronary artery before the PCI
Exclusion
- An admission electrocardiogram (ECG) showing complete left bundle branch block or a paced rhythm
- Systolic blood pressure \< 90 mmHg
- A history of coronary bypass operation
- A known allergic reaction to nitroprusside
- Chronic hemodialysis
- Intravenous drug abuse
- Pregnancy
- Rescue intervention after failed thrombolysis
- Contraindications to aspirin or clopidogrel
- Need for emergent coronary artery bypass surgery
- Inability to provide informed consent
Key Trial Info
Start Date :
January 1 2003
Trial Type :
INTERVENTIONAL
End Date :
April 1 2005
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00128791
Start Date
January 1 2003
End Date
April 1 2005
Last Update
May 25 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Soroka University Medical Center
Beersheba, Israel, 84101