Status:
COMPLETED
Adherence to Guidelines for Antibiotic Use in Respiratory Infections at Hospitals
Lead Sponsor:
Radboud University Medical Center
Conditions:
Pneumonia
Chronic Bronchitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to test a strategy to improve the quality of antibiotic use in lower respiratory tract infections (LRTIs) at hospitals. Therefore, a multifaceted intervention strategy is ...
Detailed Description
Improving processes of care in patients with hospital LRTI has been related to better patient outcome. Inappropriate use of antibiotics has contributed to the emergence and spread of drug-resistant mi...
Eligibility Criteria
Inclusion
- Patients admitted to a respiratory care or internal medicine ward with community-acquired pneumonia or acute exacerbation of chronic bronchitis or chronic obstructive pulmonary disease (COPD)
Exclusion
- Recent (\< 30 days) admission for LRTI
- Patients with underlying immunodeficiency (HIV infection, neutropenia, treatment with immunomodulating drugs, active hematological malignancies, anatomical or functional asplenia and hypogammaglobulinemia)
- Patients already on treatment with antibiotics for another culture proven infection at the time of admission
- Patients from nursing homes
- Patients who had been transferred to another hospital or ICU and patients who had died within 24 hours of admission
- Patients with very poor prognosis (life expectancy \< 2 weeks on admission).
Key Trial Info
Start Date :
September 1 2002
Trial Type :
INTERVENTIONAL
End Date :
April 1 2005
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT00129883
Start Date
September 1 2002
End Date
April 1 2005
Last Update
September 27 2005
Active Locations (7)
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1
Gelre Ziekenhuizen
Apeldoorn, Netherlands
2
Deventer Ziekenhuis
Deventer, Netherlands
3
Ziekenhuis Gelderse Vallei
Ede, Netherlands
4
Bernhoven Ziekenhuis
Oss, Netherlands