Status:
COMPLETED
Investigation of Leukocyte Trafficking Into Skin Blisters During Cardiopulmonary Bypass
Lead Sponsor:
Imperial College London
Collaborating Sponsors:
British Heart Foundation
Conditions:
Ischemic Heart Disease
Angina Pectoris
Eligibility:
All Genders
30-75 years
Phase:
NA
Brief Summary
The purpose of this study was to see if the heart-lung machine involved in cardiac surgery increases the movement of activated white blood cells from the bloodstream into the patient's tissues and als...
Detailed Description
It has long been known that exposure of blood to the heart-lung bypass machine can trigger a whole-body inflammatory response in cardiac surgery patients that is linked to activation of circulating wh...
Eligibility Criteria
Inclusion
- Primary elective coronary artery bypass surgery
Exclusion
- Emergent, urgent or re-do surgery
- Patients on oral corticosteroid medication
- Patients on aspirin therapy \< 7 days prior to operation
Key Trial Info
Start Date :
January 1 2003
Trial Type :
INTERVENTIONAL
End Date :
June 1 2005
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00131040
Start Date
January 1 2003
End Date
June 1 2005
Last Update
May 28 2015
Active Locations (1)
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1
Hammersmith Hospital
London, United Kingdom, W12 0NN