Status:
COMPLETED
Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel
Lead Sponsor:
University of Utah
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Contraception
Eligibility:
FEMALE
18-30 years
Phase:
PHASE4
Brief Summary
This study will determine the effects of St. John's wort, a common herbal remedy, on metabolism of the female contraceptive hormone levonorgestrel.
Detailed Description
In the last decade, St. John's wort has become one of the most commonly used botanicals. Levonorgestrel is a form of progesterone, a female hormone involved in conception. It can be given as both a pi...
Eligibility Criteria
Inclusion
- Body mass index (BMI) between 20 and 25
- Regular menstrual cycles for at least 3 months prior to study entry
Exclusion
- Current use of foods, herbs, vitamins, over-the-counter supplements, or any medications that could alter pharmacokinetics of other drugs
- Medical contraindications to the use of contraceptives
Key Trial Info
Start Date :
August 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2008
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00131885
Start Date
August 1 2005
End Date
May 1 2008
Last Update
November 13 2023
Active Locations (1)
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1
University of Utah
Salt Lake City, Utah, United States, 84112