Status:
COMPLETED
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Ovarian Neoplasms
Colorectal Neoplasms
Eligibility:
All Genders
19+ years
Brief Summary
Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy. The tissue obtained will be used to determine ho...
Detailed Description
The goal of this study is to determine if concepts established in mouse models of the tumor microvascular response to ionizing radiation (IR) therapy are applicable to human tumors in order to begin t...
Eligibility Criteria
Inclusion
- Patients who are felt to have adequate tumor volume for these studies, at least a 2 x 2 x 2 cm3 tumor by physical exam, imaging studies or colonoscopy reports
- Primary or recurrent tumors are eligible
- Patients must be suitable candidates for surgery
- Patients who have signed the informed consent
Exclusion
- Patients who are not considered suitable candidates for surgery
- Patients who have received prior radiation therapy to the tumor being removed
- Patients who have received chemotherapy within 6 months of tumor removal
- Patients who are pregnant
- Patients may choose to be excluded at any time
- Minors are excluded from this study because there are expected to be very few minors with the tumor types which the investigators are evaluating in this study
Key Trial Info
Start Date :
August 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
149 Patients enrolled
Trial Details
Trial ID
NCT00132704
Start Date
August 1 2004
End Date
July 1 2014
Last Update
July 24 2014
Active Locations (1)
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1
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10065