Status:

TERMINATED

The Timing of Prophylactic Antibiotics in Cesarean Section and the Risk of Post-operative Febrile Morbidity

Lead Sponsor:

University of Pennsylvania

Conditions:

Cesarean Section

Eligibility:

FEMALE

Phase:

PHASE4

Brief Summary

The purpose of this study is to determine whether the timing of prophylactic antibiotic administration for cesarean section (immediate preoperative versus intraoperative administration) impacts the ra...

Eligibility Criteria

Inclusion

  • Gestational age \> 36 weeks
  • Ability to understand requirements of the study
  • Elective/non-emergent cesarean section selected as route of delivery by treating physicians

Exclusion

  • Known fetal anomaly
  • Exposure to antibiotics within 7 days of admission, including intrapartum group B streptococcal (GBS) prophylaxis
  • Emergent cesarean delivery (i.e. for fetal distress, maternal distress, obstetric hemorrhage)
  • Overt maternal intrapartum infection requiring antibiotics
  • Prolonged rupture of membranes (\>18 hours)

Key Trial Info

Start Date :

July 1 2004

Trial Type :

INTERVENTIONAL

End Date :

July 1 2006

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00133029

Start Date

July 1 2004

End Date

July 1 2006

Last Update

August 15 2016

Active Locations (1)

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1

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104