Status:
COMPLETED
The Effects of Calorie Restriction With or Without Metformin on Weight and Insulin Resistance
Lead Sponsor:
University Hospital, Ghent
Conditions:
Body Weight
Insulin Resistance
Eligibility:
All Genders
20-55 years
Phase:
PHASE4
Brief Summary
This is a study to: * Determine the difference between strong hypo-energetic "standard diet advice" and modest hypo-energetic "personal diet advice"; and * Determine the influence of insulin-insensit...
Detailed Description
The aim of the present study was to determine what the difference is of a strong hypo-energetic "standard diet advice" and a modest hypo-energetic "personal diet advice" which was determined by the en...
Eligibility Criteria
Inclusion
- 20-55 years of age
- Body mass index (BMI) equal to or greater than 30 kg/m²
- Insulin resistance as determined by oral glucose tolerance test (OGTT) and HOMA
Exclusion
- Diabetes mellitus, kidney insufficiency, or hepatic insufficiency
- Hypogonadism with other etiology than overweight
- Pregnancy
- BMI equal to or greater than 40 kg/m²
Key Trial Info
Start Date :
January 1 2002
Trial Type :
INTERVENTIONAL
End Date :
May 1 2004
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT00134290
Start Date
January 1 2002
End Date
May 1 2004
Last Update
December 28 2007
Active Locations (1)
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1
University Hospital Ghent
Ghent, Belgium, 9000