Status:
COMPLETED
Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia
Lead Sponsor:
Pfizer
Conditions:
Hypercholesterolemia, Familial
Hyperlipidemia
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To evaluate the efficacy and safety of torcetrapib/atorvastatin compared to atorvastatin alone in patients with hete...
Detailed Description
For additional information please call: 1-800-718-1021
Eligibility Criteria
Inclusion
- Diagnosis of Heterozygous Familial Hypercholesterolemia
- At least 18 years of age
Exclusion
- Women who are pregnant or lactating, or planning to become pregnant.
- Subjects with a clinically indicated need for statin (HMG-CoA reductase inhibitor) therapy other than atorvastatin or other concomitant therapy with known lipid altering effects on LDL-C and HDL-C including fibrates and nicotinic acid (high doses)
- Subjects taking any drugs known to be associated with an increased risk of myositis in combination with HMG-CoA reductase inhibitors
- Subjects with any other medical condition or laboratory abnormality which could affect subject safety, preclude evaluation of response, or render unlikely that the subject would complete the study
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
End Date :
March 1 2006
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT00134485
Start Date
March 1 2005
End Date
March 1 2006
Last Update
October 30 2007
Active Locations (41)
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1
Pfizer Investigational Site
San Diego, California, United States, 92120
2
Pfizer Investigational Site
Washington D.C., District of Columbia, United States, 20037
3
Pfizer Investigational Site
Lutz, Florida, United States, 33549
4
Pfizer Investigational Site
Tampa, Florida, United States, 33603