Status:
COMPLETED
Study Comparing the Efficacy of Amlodipine Besylate/Benazepril Versus Amlodipine in the Treatment of Severe Hypertension
Lead Sponsor:
Novartis Pharmaceuticals
Conditions:
Hypertension
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
This trial is designed to study the efficacy of an amlodipine besylate/benazepril treatment regimen versus an amlodipine treatment regimen in the treatment of severe hypertension.
Eligibility Criteria
Inclusion
- Diagnosis of severe hypertension
Exclusion
- Diastolic blood pressure (DBP) \< 60 mm Hg
- Serum potassium \< 3.5 or \> 5.5 mEq/L in the absence of all potassium supplements
- Refractory hypertension defined as systolic blood pressure (SBP) ≥ 180 mmHg and/or DBP ≥ 110 mmHg and unresponsive to triple-drug regimens
- Other protocol-defined exclusion criteria may apply.
Key Trial Info
Start Date :
December 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2005
Estimated Enrollment :
259 Patients enrolled
Trial Details
Trial ID
NCT00136851
Start Date
December 1 2004
End Date
July 1 2005
Last Update
November 8 2011
Active Locations (1)
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1
Novartis Pharmaceuticals
East Hanover, New Jersey, United States, 07936