Status:
COMPLETED
Human Immunity to MSP-1 in Western Kenya
Lead Sponsor:
Case Western Reserve University
Collaborating Sponsors:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Plasmodium Falciparum Malaria
Eligibility:
All Genders
1+ years
Brief Summary
This is a study of 125 healthy male and female Kenyan adults aged 18 years and above, and 300 healthy male and female Kenyan infants enrolled at 1 month of age and followed to 3 years of age. Twenty h...
Detailed Description
This study will include two major populations: (1) the Adult Repeat Cross Sectional study (ARCS) will involve 125 healthy Kenya-residents male and female aged 18 years and above; and (2) the Pediatric...
Eligibility Criteria
Inclusion
- Permanent residency in the study area for ARCS study and within 50 km of Chulaimbo Rural Health Training Center for PIC study.
- Healthy by medical examination.
- Understood and signed written informed consent and is willing to participate in the study.
- ARCs study participants must be older than 18 years of age, and PIC study participants will be enrolled at 1 month and followed until 3 years of age.
- Study participant willing to attend scheduled follow up visits at clinic and willing to have field assistant make home visits during follow-up.
Exclusion
- Hemoglobin \<5 g/dl for children, \<10 g/dl for adults.
- Received a blood transfusion within the past 6 months for adults or ever for children.
- Presence or signs of severe complicated falciparum malaria (WHO, 1989).
- Women who are self-reported to be pregnant.
- Unwilling or unable to continue participation.
Key Trial Info
Start Date :
July 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
475 Patients enrolled
Trial Details
Trial ID
NCT00138372
Start Date
July 1 2004
End Date
April 1 2013
Last Update
January 20 2022
Active Locations (1)
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1
Kenya Medical Research Institute
Kisumu, Kenya