Status:
UNKNOWN
Boost Use in Breast Conservation Radiotherapy
Lead Sponsor:
St George Hospital, Australia
Conditions:
Breast Neoplasms
Eligibility:
FEMALE
18+ years
Phase:
PHASE3
Brief Summary
This is a two arm randomized study for patients who are undergoing radiotherapy following breast conservation surgery for breast cancer. Local recurrence of breast cancer will be compared for patients...
Detailed Description
A boost dose of radiation is commonly but not universally employed in breast conservation techniques. The potential disadvantages when a boost is employed include: * Increased complexity of treatmen...
Eligibility Criteria
Inclusion
- Histologically proven carcinoma of the breast, T1-2 (0-5cm) N0-1, M0.
- Pure ductal carcinoma in situ accepted if completely excised.
- Any receptor status.
- Extensive intraductal cancer (EIC) accepted if completely excised.
Exclusion
- Unable to consent
- Vascular/collagen disorder
- Prior malignancy except minor skin squamous cell or basal cell carcinoma or carcinoma in-situ of the cervix .
- Gross multifocal disease
- Involvement of margins.
- Bilateral breast cancer
Key Trial Info
Start Date :
January 1 1997
Trial Type :
INTERVENTIONAL
End Date :
December 1 2015
Estimated Enrollment :
680 Patients enrolled
Trial Details
Trial ID
NCT00138814
Start Date
January 1 1997
End Date
December 1 2015
Last Update
December 15 2005
Active Locations (3)
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1
Liverpool Hospital
Sydney, New South Wales, Australia, 2170
2
Cancer Care Centre, St George Hospital
Sydney, New South Wales, Australia, 2217
3
Wollongong Hospital
Wollongong, New South Wales, Australia, 2500