Status:
COMPLETED
Intracellular and Renal/Myocardial Tissue Concentrations of Cyclosporine A (CsA) and Rejection Frequency Following Transplantation
Lead Sponsor:
University of Oslo School of Pharmacy
Conditions:
Renal Transplantation
Heart Transplantation
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The primary objective is to investigate intralymphocyte concentrations of CsA in renal and heart transplant recipients to elucidate the association between the intracellular concentration and efficacy...
Detailed Description
The primary objective is to investigate intralymphocyte concentrations of CsA in renal and heart transplant recipients to elucidate the association between the intracellular concentration and efficacy...
Eligibility Criteria
Inclusion
- Renal or heart transplant recipients scheduled to receive CsA as part of their immunosuppressive therapy at the time of transplantation.
- 18 years of age or older.
- Signed informed consent.
Exclusion
- Known contraindications for renal or heart biopsies, respectively, at the time of inclusion.
- Concomitant treatment with: diltiazem, verapamil, phenytoin, carbamazepine, fluconazole, ketoconazole, erythromycin, clarithromycin.
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
End Date :
September 1 2006
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00139009
Start Date
June 1 2005
End Date
September 1 2006
Last Update
June 15 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Rikshospitalet, Section of Nephrology
Oslo, Oslo County, Norway, 0027