Status:
COMPLETED
A Study to Compare the Efficacy of Hepatitis A Vaccine and Immune Globulin When Given After Exposure to Hepatitis A
Lead Sponsor:
Centers for Disease Control and Prevention
Collaborating Sponsors:
University of Michigan
Ministry of Health, Kazakhstan
Conditions:
Hepatitis A
Eligibility:
All Genders
2-40 years
Phase:
NA
Brief Summary
Immune globulin is effective about 85% of the time in preventing hepatitis A in people who have been exposed, if it is given within 14 days of exposure. Several lines of evidence suggest that hepatiti...
Detailed Description
Title: An Epidemiologic Study of Hepatitis A Vaccine for Postexposure Prophylaxis Clinical Phase: Investigation of an application unrelated to original approved use. Primary Objective: To compare the...
Eligibility Criteria
Inclusion
- Exposure to an index case of hepatitis A within 14 days of onset of illness; at least 2 years and no more than 40 years of age at time of study entry; susceptible to hepatitis A; give informed consent or have informed consent given by a responsible parent/guardian -
Exclusion
- history of hepatitis A; prior receipt of hepatitis A vaccine; receipt of immune globulin within 180 days before study entry; evidence of liver disease; receipt of any live virus vaccine within 21 days prior to study entry; moderate or severe intercurrent illness or axillary temperature of 37.5 degrees or higher at time of study entry; various other medical conditions;
- \-
Key Trial Info
Start Date :
September 1 2003
Trial Type :
INTERVENTIONAL
End Date :
May 1 2005
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT00139139
Start Date
September 1 2003
End Date
May 1 2005
Last Update
January 13 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Sanitary EpidemiologyAuthority
Almaty, Kazakhstan