Status:
COMPLETED
Radial Artery Versus Saphenous Vein Patency (RSVP) Study
Lead Sponsor:
Imperial College London
Collaborating Sponsors:
The Royal College of Surgeons of England
Royal Brompton & Harefield NHS Foundation Trust
Conditions:
Coronary Arteriosclerosis
Eligibility:
All Genders
40-70 years
Phase:
PHASE3
Brief Summary
The purpose of this study is to determine whether the radial artery (artery in the arm) or saphenous vein (vein in the leg), when used as bypass grafts for coronary artery bypass surgery, have a great...
Detailed Description
Arteries differ from veins both in morphology and physiology. Thus the way they behave as in vivo conduits when used in coronary artery bypass grafting is also likely to be different. This may partly ...
Eligibility Criteria
Inclusion
- on waiting list for clinically-indicated myocardial revascularization surgery
- aged 40-70 years
- significant stenosis (≥70%) in the circumflex territory as identified on preoperative angiograms
- negative Allen's test (defined as the return of palmar circulation within 5 seconds of releasing ulnar artery compression)
- willing to give written informed consent
Exclusion
- poor left ventricular (LV) function (LV ejection fraction \<25%)
- severe diffuse peripheral vascular disease or bilateral varicose venous disease
- inability to comply with the angiographic follow-up at 3 months or/and 5 years
Key Trial Info
Start Date :
May 1 1998
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2006
Estimated Enrollment :
142 Patients enrolled
Trial Details
Trial ID
NCT00139399
Start Date
May 1 1998
End Date
November 1 2006
Last Update
June 25 2019
Active Locations (1)
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1
Royal Brompton & Harefield NHS Trust
London, United Kingdom, SW3 6NP